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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD2
All Species:
3.33
Human Site:
S544
Identified Species:
12.22
UniProt:
Q9BYW2
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYW2
NP_054878.5
2564
287550
S544
L
G
F
R
R
G
S
S
Y
S
K
H
D
S
S
Chimpanzee
Pan troglodytes
XP_516423
2549
285788
S535
S
S
Y
S
K
H
D
S
S
A
S
R
Y
K
S
Rhesus Macaque
Macaca mulatta
XP_001113652
2550
286209
S531
F
R
R
G
S
S
Y
S
K
H
D
S
S
A
S
Dog
Lupus familis
XP_864158
2562
287091
S540
E
L
G
F
R
R
G
S
S
Y
S
K
H
D
N
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418510
2354
262767
Q405
K
T
L
S
P
L
N
Q
L
N
D
S
P
T
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783359
3042
342758
R589
R
R
G
R
S
G
S
R
E
R
R
R
Y
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q2LAE1
1759
193210
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
96.9
92
N.A.
N.A.
N.A.
N.A.
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
24.7
Protein Similarity:
100
98.9
98
94.6
N.A.
N.A.
N.A.
N.A.
N.A.
71.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
41.6
P-Site Identity:
100
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
33.3
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
15
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
15
0
0
0
29
0
15
15
15
% D
% Glu:
15
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% E
% Phe:
15
0
15
15
0
0
0
0
0
0
0
0
0
0
15
% F
% Gly:
0
15
29
15
0
29
15
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
15
0
0
0
15
0
15
15
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
15
0
0
0
15
0
0
0
15
0
15
15
0
15
0
% K
% Leu:
15
15
15
0
0
15
0
0
15
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
15
0
0
15
0
0
0
0
15
% N
% Pro:
0
0
0
0
15
0
0
0
0
0
0
0
15
0
0
% P
% Gln:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% Q
% Arg:
15
29
15
29
29
15
0
15
0
15
15
29
0
15
0
% R
% Ser:
15
15
0
29
29
15
29
58
29
15
29
29
15
15
43
% S
% Thr:
0
15
0
0
0
0
0
0
0
0
0
0
0
15
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
0
0
0
15
0
15
15
0
0
29
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _